Established in 1989, Southwest Independent Institutional Review Board, Inc. (SIIRB) is a national Institutional Review Board (IRB) specializing in the review of Ophthalmic research.  SIIRB consists of a unique, diverse group of individuals bound by the commitment to protect the rights and welfare of clinical research subjects by ensuring compliance with all applicable federal and state regulations, including Food and Drug Administration (FDA) and the Office of Human Research Protection (OHRP) guidance. SIIRB abides by the International Committee on Harmonisation (ICH) Guidelines and Good Clinical Practice (GCP) guidelines. These members are highly qualified with significant knowledge and experience in ethical principles, legal precedents and scientific methodology.  In addition the board has consulting Ophthalmologist in each subspecialty.